Ligands for glutamate receptors:: Design and therapeutic prospects

被引:522
作者
Bräuner-Osborne, H
Egebjerg, J
Nielsen, EO
Madsen, U
Krogsgaard-Larsen, P
机构
[1] Royal Danish Sch Pharm, Dept Med Chem, NeuroSci PharmaBiotec Res Ctr, DK-2100 Copenhagen, Denmark
[2] Aarhus Univ, Dept Mol & Struct Biol, DK-8000 Aarhus, Denmark
[3] NeuroSearch AS, Dept Neurochem, DK-2750 Ballerup, Denmark
关键词
D O I
10.1021/jm000007r
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
[No abstract available]
引用
收藏
页码:2609 / 2645
页数:37
相关论文
共 418 条
  • [41] Comparative effect of L-CCG-I, DCG-IV and γ-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes
    Brabet, I
    Parmentier, ML
    De Colle, C
    Bockaert, J
    Acher, F
    Pin, JP
    [J]. NEUROPHARMACOLOGY, 1998, 37 (08) : 1043 - 1051
  • [42] Pharmacology of (S)-homoquisqualic acid and (S)-2-amino-5-phosphonopentanoic acid [(S)-AP5] at cloned metabotropic glutamate receptors
    Bräuner-Osborne, H
    Krogsgaard-Larsen, P
    [J]. BRITISH JOURNAL OF PHARMACOLOGY, 1998, 123 (02) : 269 - 274
  • [43] Molecular pharmacology of homologues of ibotenic acid at cloned metabotropic glutamic acid receptors
    Bräuner-Osborne, H
    Nielsen, B
    Krogsgaard-Larsen, P
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1998, 350 (2-3) : 311 - 316
  • [44] The agonist-binding domain of the calcium-sensing receptor is located at the amino-terminal domain
    Bräuner-Osborne, H
    Jensen, AA
    Sheppard, PO
    O'Hara, P
    Krogsgaard-Larsen, P
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (26) : 18382 - 18386
  • [45] Bräuner-Osborne H, 1999, NEUROREPORT, V10, P3923
  • [46] A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid
    Brauner-Osborne, H
    Slok, FA
    Skjaerbaek, N
    Ebert, B
    Sekiyama, N
    Nakanishi, S
    KrogsgaardLarsen, P
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (16) : 3188 - 3194
  • [47] New analogues of ACPD with selective activity for group II metabotropic glutamate receptors
    Brauner-Osborne, H
    Madsen, U
    MikiciukOlasik, E
    Curry, K
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1997, 332 (03) : 327 - 331
  • [48] Molecular pharmacology of 4-substituted glutamic acid analogues at ionotropic and metabotropic excitatory amino acid receptors
    Brauner-Osborne, H
    Nielsen, B
    Stensbol, TB
    Johansen, TN
    Skjaerbaek, N
    KrogsgaardLarsen, P
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1997, 335 (2-3) : R1 - R3
  • [49] THE CA2+ INFLUX INDUCED BY BETA-AMYLOID PEPTIDE-25-35 IN CULTURED HIPPOCAMPAL-NEURONS RESULTS FROM NETWORK EXCITATION
    BRORSON, JR
    BINDOKAS, VP
    IWAMA, T
    MARCUCCILLI, CJ
    CHISHOLM, JC
    MILLER, RJ
    [J]. JOURNAL OF NEUROBIOLOGY, 1995, 26 (03): : 325 - 338
  • [50] BROSE N, 1993, J BIOL CHEM, V268, P22663