Alkaloids with antioxidant activities from Aconitum handelianum

被引:46
作者
Yin, Tian-Peng [1 ]
Cai, Le [1 ]
Xing, Yun [1 ]
Yu, Jing [1 ]
Li, Xue-Jiao [1 ]
Mei, Rui-Feng [1 ]
Ding, Zhong-Tao [1 ]
机构
[1] Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resource, Kunming 650091, Peoples R China
基金
中国国家自然科学基金;
关键词
Aconitum handelianum; Ranunculaceae; diterpenoid alkaloid; handelidine; antioxidant; DITERPENOID ALKALOIDS; NORDITERPENOID ALKALOIDS; ROOTS; CONSTITUENTS; REVISION; LAEVE;
D O I
10.1080/10286020.2015.1114473
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A new C-20-diterpenoid alkaloid handelidine (1) and twenty-seven known alkaloids (2-28) were isolated from the roots of Aconitum handelianum. Their structures were established on the basis of extensive spectroscopic analyses. The study indicated that denudatine-type C-20-diterpenoid alkaloids with vicinal-triol system and benzyltetrahydroisoquinoline alkaloids exhibited significant antioxidant activities measured by three antioxidant test systems. The aconitine-type C-19-diterpenoid alkaloids could serve as potential secondary antioxidants for their strong binding effects to metal ions.
引用
收藏
页码:603 / 610
页数:8
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