Alkaloids with antioxidant activities from Aconitum handelianum

被引：46

作者：

Yin, Tian-Peng ^{[1
]}

Cai, Le ^{[1
]}

Xing, Yun ^{[1
]}

Yu, Jing ^{[1
]}

Li, Xue-Jiao ^{[1
]}

Mei, Rui-Feng ^{[1
]}

Ding, Zhong-Tao ^{[1
]}

机构：

[1] Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resource, Kunming 650091, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2016年 / 18卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Aconitum handelianum; Ranunculaceae; diterpenoid alkaloid; handelidine; antioxidant; DITERPENOID ALKALOIDS; NORDITERPENOID ALKALOIDS; ROOTS; CONSTITUENTS; REVISION; LAEVE;

D O I：

10.1080/10286020.2015.1114473

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new C-20-diterpenoid alkaloid handelidine (1) and twenty-seven known alkaloids (2-28) were isolated from the roots of Aconitum handelianum. Their structures were established on the basis of extensive spectroscopic analyses. The study indicated that denudatine-type C-20-diterpenoid alkaloids with vicinal-triol system and benzyltetrahydroisoquinoline alkaloids exhibited significant antioxidant activities measured by three antioxidant test systems. The aconitine-type C-19-diterpenoid alkaloids could serve as potential secondary antioxidants for their strong binding effects to metal ions.

引用

页码：603 / 610

页数：8

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