The effects of hcy on the expression of cox-2 and 5-lox in experimental colitis rats model

被引:0
|
作者
Wang, Jing [1 ]
机构
[1] Anhui Med Univ, Affiliated Hosp 1, Hefei, Anhui, Peoples R China
关键词
Homocysteine; Inflammatory bowel disease; Cyclooxygenase-2; 5-Lipoxygenase; Nuclear factor kappa B; Leukotrienes; Prostaglandin E2;
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
PP 0312
引用
收藏
页码:230 / 230
页数:1
相关论文
共 50 条
  • [41] Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice
    Bitto, Alessandra
    Giuliani, Daniela
    Pallio, Giovanni
    Irrera, Natasha
    Vandini, Eleonora
    Canalini, Fabrizio
    Zaffe, Davide
    Ottani, Alessandra
    Minutoli, Letteria
    Rinaldi, Mariagrazia
    Guarini, Salvatore
    Squadrito, Francesco
    Altavilla, Domenica
    INFLAMMATION RESEARCH, 2017, 66 (05) : 389 - 398
  • [42] Design, synthesis and evaluation of novel diaryl-1,5-diazoles derivatives bearing morpholine as potent dual COX-2/5-LOX inhibitors and antitumor agents
    Li, Zhang
    Wang, Zhong-Chang
    Li, Xin
    Abbas, Muhammad
    Wu, Song-Yu
    Ren, Shen-Zhen
    Liu, Qi-Xing
    Liu, Yi
    Chen, Peng-Wen
    Duan, Yong-Tao
    Lv, Peng-Cheng
    Zhu, Hai-Liang
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 169 : 168 - 184
  • [43] A novel class of tyrosine derivatives as dual 5-LOX and COX-2/mPGES1 inhibitors with PGE2 mediated anticancer properties
    Puratchikody, Ayarivan
    Umamaheswari, Appavoo
    Irfan, Navabshan
    Sinha, Shweta
    Manju, S. L.
    Ramanan, Meera
    Ramamoorthy, Gayathri
    Doble, Mukesh
    NEW JOURNAL OF CHEMISTRY, 2019, 43 (02) : 834 - 846
  • [44] Inhibition of COX-2 and 5-LOX regulates the progression of colorectal cancer by promoting PTEN and suppressing PI3K/AKT pathway
    Chang, Jian
    Tang, Nan
    Fang, Qi
    Zhu, Kongfan
    Liu, Lei
    Xiong, Xingcheng
    Zhu, Zhongchao
    Zhang, Bixiang
    Zhang, Mingzhi
    Tao, Jing
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 517 (01) : 1 - 7
  • [45] Synthesis and Anti-proliferative Activity of Indole-2-amide Derivatives as Cyclooxygenase-2/5-lipoxygenase (COX-2/5-LOX) Dual Inhibitors
    Qian, Shihu
    Huang, Yuanzheng
    Li, Jiaming
    Zhang, Yanchun
    Zhang, Bin
    Jin, Fan
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 41 (04) : 1631 - 1638
  • [46] Novel approach of multi-targeted thiazoles and thiazolidenes toward anti-inflammatory and anticancer therapy-dual inhibition of COX-2 and 5-LOX enzymes
    Jacob, Jaismy
    Manju, S. L.
    MEDICINAL CHEMISTRY RESEARCH, 2021, 30 (01) : 236 - 257
  • [47] Effects of selective Cox-2 inhibitor, rofecoxib, alone or combination with furosemide on renal functions and renal Cox-2 expression in rats
    Kose, Fatih
    Besen, Ayberk
    Paydas, Saime
    Balal, Mustafa
    Gonlusen, Gulfiliz
    Inal, Tamer
    Dogan, Ayse
    Kibar, Mustafa
    CLINICAL AND EXPERIMENTAL NEPHROLOGY, 2010, 14 (01) : 22 - 27
  • [48] Effect of COX-2 inhibitor after TNBS-induced colitis in wistar rats
    Ribeiro Paiotti, Ana Paula
    Miszputen, Sender Jankiel
    Fujiyama Oshima, Celina Tizuko
    Costa, Henrique de Oliveira
    Ribeiro, Daniel Araki
    Franco, Marcello
    JOURNAL OF MOLECULAR HISTOLOGY, 2009, 40 (04) : 317 - 324
  • [49] Inhibitory effects of etodolac, a selective COX-2 inhibitor, on the occurrence of tumors in colitis-induced tumorigenesis model in rats
    Takeda, J
    Kitajima, K
    Fujii, S
    Horiuchi, H
    Hori, H
    Chibana, Y
    Okuyama, T
    Tominaga, K
    Ichikawa, K
    Ono, Y
    Teramoto, T
    Ohkura, Y
    Imura, J
    Shinoda, M
    Chiba, T
    Sakamoto, C
    Kawamata, H
    Fujimori, T
    ONCOLOGY REPORTS, 2004, 11 (05) : 981 - 985
  • [50] Serum Vascular Endothelial Growth Factor and COX-2/5-LOX Inhibition in Advanced Non-small Cell Lung Cancer Cancer and Leukemia Group B 150304
    Edelman, Martin J.
    Hodgson, Lydia
    Wang, Xiaofei
    Christenson, Robert
    Jewell, Scott
    Vokes, Everett
    Kratzke, Robert
    JOURNAL OF THORACIC ONCOLOGY, 2011, 6 (11) : 1902 - 1906