MULTIDRUG-RESISTANT ENTEROCOCCUS FAECIUM MENINGITIS IN A TODDLER CHARACTERIZATION OF THE ORGANISM AND SUCCESSFUL TREATMENT WITH INTRAVENTRICULAR DAPTOMYCIN AND INTRAVENOUS TIGECYCLINE

被引：55
作者：
Jaspan, Heather B. [1 ,2 ]
Brothers, Adam W. [1 ]
Campbell, Angela J. P. [1 ,2 ,3 ]
McGuire, John K. [1 ,2 ]
Browd, Samuel R. [4 ]
Manley, Thomas J. [1 ,3 ]
Pak, Daniel [2 ]
Weissman, Scott J. [1 ,2 ]
机构：
[1] Seattle Childrens Hosp, Dept Pediat, Seattle, WA 98105 USA
[2] Univ Washington, Dept Pediat, Seattle, WA 98195 USA
[3] Fred Hutchinson Canc Res Inst, Seattle, WA USA
[4] Seattle Childrens Hosp, Dept Neurol Surg, Seattle, WA USA
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2010年 / 29卷 / 04期
关键词：
vancomycin-resistant Enterococcus; tigecycline; daptomycin; meningitis; children; DAPTOMYCIN; VANCOMYCIN; VENTRICULITIS;
D O I：
10.1097/INF.0b013e3181c806d8
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A case of enterococcal meningitis in a toddler is presented. The organism was highly resistant to all drugs previously used for pediatric Gram-positive meningitis. She was successfully treated with intraventricular and intravenous daptomycin and intravenous tigecycline. The organism was characterized as a member of CC17, a notorious emerging nosocomial clone of Enterococcus faecium.
引用
收藏
页码：379 / 381
页数：3
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