The first case of acinic cell carcinoma of the breast within a fibroadenoma: Case report

被引:8
|
作者
Limite, G. [1 ]
Di Micco, R. [1 ]
Esposito, E. [1 ]
Sollazzo, V. [1 ]
Cervotti, M. [1 ]
Pettinato, G. [2 ]
Varone, V. [2 ]
Benassai, G. [1 ]
Monda, A. [1 ]
Luglio, G. [1 ]
Maisto, V. [1 ]
Izzo, G. [1 ]
Forestieri, P. [1 ]
机构
[1] Univ Naples Federico II, Dept Clin Med & Surg, Breast Unit, I-80131 Naples, Italy
[2] Univ Naples Federico II, Dept Adv Biomed Sci, I-80131 Naples, Italy
关键词
Acinic cell carcinoma; Breast cancer; Eosinophilic cytoplasmic granules; SECRETORY CARCINOMA; VARIANT;
D O I
10.1016/j.ijsu.2014.05.005
中图分类号
R61 [外科手术学];
学科分类号
摘要
A case of acinic cell carcinoma of the breast is reported in a 26-year-old woman. She presented a lump in her right breast, that seemed to be a fibroadenoma. The open biopsy revealed a well-bordered fibroadenoma, together with a proliferation of cells characterized by serous acinar differentiation and eosinophilic cytoplasmic granules. Tumor cells stained for amylase, lysozyme, alpha-1-antichymotripsin, epithelial membrane antigen, S-100 protein, pan-cytokeratin, cytokeratin 7 and E-cadherin. Estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2 overexpression, CD10, P63, smooth muscle actin, cytokeratin 5/6 were negative. The sentinel node was negative. 8 months after surgery she is in good clinical conditions without recurrence or metastases. (C) 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:S232 / S235
页数:4
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