Resolution of Two Steps in Botulinum Neurotoxin Serotype A1 Light Chain Localization to the Intracellular Plasma Membrane

被引:0
作者
Gardner, Alexander [1 ]
Tepp, William H. [2 ]
Bradshaw, Marite [2 ]
Barbieri, Joseph T. [1 ]
Pellett, Sabine [2 ]
机构
[1] Med Coll Wisconsin, Dept Microbiol & Immunol, Milwaukee, WI 53226 USA
[2] Univ Wisconsin Madison, Dept Bacteriol, Madison, WI USA
基金
美国国家卫生研究院;
关键词
Botulinum neurotoxin; Botulinum neurotoxin serotype A1; Botulinum neurotoxin serotype A3; Cellular microbiology; SNAP-25; Toxins; CLOSTRIDIUM-BOTULINUM; PURIFICATION;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:S20 / S21
页数:2
相关论文
共 14 条
[1]   Holotoxin Activity of Botulinum Neurotoxin Subtype A4 Originating from a Nontoxigenic Clostridium botulinum Expression System [J].
Bradshaw, Marite ;
Tepp, William H. ;
Whitemarsh, Regina C. M. ;
Pellett, Sabine ;
Johnson, Eric A. .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2014, 80 (23) :7415-7422
[2]   Association of Botulinum Neurotoxin Serotype A Light Chain with Plasma Membrane-bound SNAP-25 [J].
Chen, Sheng ;
Barbieri, Joseph T. .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (17) :15067-15072
[3]   HHV-7 U21 exploits Golgi quality control carriers to reroute class I MHC molecules to lysosomes [J].
Dirck, Aaron T. ;
Whyte, Melissa L. ;
Hudson, Amy W. .
MOLECULAR BIOLOGY OF THE CELL, 2020, 31 (03) :196-208
[4]   Purification, Modeling, and Analysis of Botulinum Neurotoxin Subtype A5 (BoNT/A5) from Clostridium botulinum Strain A661222 [J].
Jacobson, Mark J. ;
Lin, Guangyun ;
Tepp, William ;
Dupuy, Jerome ;
Stenmark, Pal ;
Stevens, Raymond C. ;
Johnson, Eric A. .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2011, 77 (12) :4217-4222
[5]   Clostridium botulinum and its neurotoxins:: a metabolic and cellular perspective [J].
Johnson, EA ;
Bradshaw, M .
TOXICON, 2001, 39 (11) :1703-1722
[6]   Isolation and Functional Characterization of the Novel Clostridium botulinum Neurotoxin A8 Subtype [J].
Kull, Skadi ;
Schulz, K. Melanie ;
Strotmeier, Jasmin Weisemann Nee ;
Kirchner, Sebastian ;
Schreiber, Tanja ;
Bollenbach, Alexander ;
Dabrowski, P. Wojtek ;
Nitsche, Andreas ;
Kalb, Suzanne R. ;
Dorner, Martin B. ;
Barr, John R. ;
Rummel, Andreas ;
Dorner, Brigitte G. .
PLOS ONE, 2015, 10 (02)
[7]  
Malizio CJ, 2000, METH MOL B, V145, P27
[8]   The Light Chain Defines the Duration of Action of Botulinum Toxin Serotype A Subtypes [J].
Pellett, Sabine ;
Bradshaw, Marite ;
Tepp, William H. ;
Pier, Christina L. ;
Whitemarsh, Regina C. M. ;
Chen, Chen ;
Barbieri, Joseph T. ;
Johnson, Eric A. .
MBIO, 2018, 9 (02)
[9]   Neurotoxins affecting neuroexocytosis [J].
Schiavo, G ;
Matteoli, M ;
Montecucco, C .
PHYSIOLOGICAL REVIEWS, 2000, 80 (02) :717-766
[10]  
SCHIAVO G, 1992, J BIOL CHEM, V267, P23479