Are Metformin Doses Used in Murine Cancer Models Clinically Relevant?

被引:135
作者
Chandel, Navdeep S. [1 ]
Avizonis, Dania [2 ]
Reczek, Colleen R. [1 ]
Weinberg, Samuel E. [1 ]
Menz, Stephan [4 ]
Neuhaus, Roland [4 ]
Christian, Sven [3 ]
Haegebarth, Andrea [3 ]
Algire, Carolyn [3 ]
Pollak, Michael [2 ]
机构
[1] Northwestern Univ, Dept Med, Feinberg Sch Med, Chicago, IL 60611 USA
[2] McGill Univ, Goodman & Segal Canc Ctr, 3755 Cote St Catherine Rd, Montreal, PQ H3T 1E2, Canada
[3] Bayer Pharma AG, Global Therapeut Res Grp Oncol 2, GDD, BPH, Mullerstr 178, D-13353 Berlin, Germany
[4] Bayer Pharma AG, DMPK, Global Early Dev, GDD,BPH, Mullerstr 178, D-13353 Berlin, Germany
关键词
BIGUANIDES; GROWTH;
D O I
10.1016/j.cmet.2016.03.010
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:569 / 570
页数:2
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