Reducing the neglected burden of viral hepatitis in Africa: Strategies for a global approach

被引:88
作者
Lemoine, Maud [1 ]
Eholie, Serge [2 ,3 ]
Lacombe, Karine [4 ,5 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Hepatol, St Marys Hosp, London, England
[2] Treichville Univ Hosp, Infect Dis & Trop Med Unit, Abidjan, Cote Ivoire
[3] Univ Felix Houphouet Boigny, Sch Med, Dept Dermatol & Infectiol, Abidjan, Cote Ivoire
[4] St Antoine Hosp, AP HP, Dept Infect Dis & Trop Med, Paris, France
[5] Univ Paris 06, Sorbonne Univ, Inst Pierre Louis Epidemiol & Sante Publ, UMR S 1136, Paris, France
关键词
Africa; Hepatitis B; Hepatitis C; Screening; Treatment; SUB-SAHARAN AFRICA; C VIRUS-INFECTION; LIVER-CANCER; HEPATOCELLULAR-CARCINOMA; RAPID TESTS; HIV; TRANSMISSION; DISEASE; EPIDEMIOLOGY; RISK;
D O I
10.1016/j.jhep.2014.10.008
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The burden of liver disease may dramatically increase in the near future in Africa, where screening and access to care and treatment are hampered by inadequate disease surveillance, lack of high-quality tools to assess chronic liver disease, and underestimated needs for human and financial resources. Chronic hepatitis may be considered as silent and neglected killer, fuelled by many years of global inertia from stakeholders and policy makers alike. However, the global battle against viral hepatitis is facing a new era owing to the advent of highly effective drugs, innovative tools for screening and clinical follow-up, and recent signs that governments, advocacy groups and global health organizations are mobilizing to advocate universal access-to- treatment. This review details the barriers to prevention, screening and treatment of viral hepatitis on the African continent, focuses on the urgent need for operational and research programmes, and suggests integrated ways to tackle the global epidemic. (C) 2014 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:469 / 476
页数:8
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