Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice

被引：6

作者：

Zhang, Yang ^{[1
]}

Zhang, Tao ^{[1
]}

Yang, Wenbo ^{[1
]}

Chen, Hongze ^{[1
]}

Geng, Xinglong ^{[1
]}

Li, Guanqun ^{[1
]}

Chen, Hua ^{[1
]}

Wang, Yongwei ^{[1
]}

Li, Le ^{[1
,2
]}

Sun, Bei ^{[1
,2
]}

机构：

[1] Harbin Med Univ, Affiliated Hosp 1, Dept Pancreat & Biliary Surg, Harbin, Peoples R China

[2] Minist Educ, Key Lab Hepatosplen Surg, Harbin, Peoples R China

来源：

FRONTIERS IN ONCOLOGY | 2021年 / 11卷

基金：

中国国家自然科学基金;

关键词：

diet; ketogenic diet; low-sugar diet; Mediterranean diet; pancreatic cancer; RESTRICTED KETOGENIC DIET; SUGAR-SWEETENED FOODS; E DELTA-TOCOTRIENOL; MEDITERRANEAN DIET; GLYCEMIC LOAD; RISK-FACTORS; VITAMIN-E; IN-VITRO; PHARMACOLOGICAL ASCORBATE; CALORIE RESTRICTION;

D O I：

10.3389/fonc.2021.630972

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Pancreatic cancer (PC) is a malignant tumor with high invasiveness, easy metastatic ability, and chemoresistance. Patients with PC have an extremely low survival rate due to the difficulty in early diagnosis. It is estimated that nearly 90% of PC cases are caused by environmental risk factors. Approximately 50% of PC cases are induced by an unhealthy diet, which can be avoided. Given this large attribution to diet, numerous studies have assessed the relationship between various dietary factors and PC. This article reviews three beneficial diets: a ketogenic diet (KD), a Mediterranean diet (MD), and a low-sugar diet. Their composition and impact mechanism are summarized and discussed. The associations between these three diets and PC were analyzed, and we aimed to provide more help and new insights for the prevention and treatment of PC.

引用

页数：14

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