Neurological pathogenesis of SARS-CoV-2 (COVID-19): from virological features to clinical symptoms

被引:10
作者
Kase, Yoshitaka [1 ,2 ]
Okano, Hideyuki [1 ]
机构
[1] Keio Univ, Sch Med, Dept Physiol, Shinjuku Ku, 35 Shinanomachi, Tokyo 1608582, Japan
[2] Univ Tokyo, Grad Sch Med, Dept Geriatr Med, Bunkyo Ku, Tokyo 1138655, Japan
关键词
Coronavirus (CoV); COVID-19; Neural disorder; SARS-CoV-2; SYNDROME CORONAVIRUS INFECTION; VIRUS; RECEPTOR; BRAIN; IDENTIFICATION; ENCEPHALITIS; CELLS; ACE2; HKU1;
D O I
10.1186/s41232-021-00165-8
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Since the worldwide outbreak of coronavirus disease 2019 (COVID-19) in 2020, various research reports and case reports have been published. It has been found that COVID-19 causes not only respiratory disorders but also thrombosis and gastrointestinal disorders, central nervous system (CNS) disorders, and peripheral neuropathy. Compared to other disorders, there are low number of research reports and low number of summaries on COVID-19-related neural disorders. Therefore, focusing on neural disorders, we outline both basic research and clinical manifestations of COVID-19-related neural disorders.
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页数:7
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