The induction of N-methyl-D-aspartate receptor-dependent long-term potentiation

被引:31
作者
Collingridge, GL [1 ]
机构
[1] Univ Bristol, Sch Med Sci, Dept Anat, MRC Ctr Synapt Plast, Bristol BS8 1TD, Avon, England
关键词
long-term potentiation; N-methyl-D-aspartate; hippocampus; synaptic plasticity; magnesium; glutamate;
D O I
10.1098/rstb.2002.1241
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The role of N-methyl-D-aspartate (NMDA) receptors in the induction of long-term potentiation (LTP) was established during the 1980s. In this article I present a personal reflection upon the role that my colleagues and I played in the discovery of the mechanism of induction of NMDA receptor-dependent LTP.
引用
收藏
页码:635 / 641
页数:7
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