Synthesis of pyrazolo[1,5-a]pyrimidines in the reaction of 5-amino-3-arylpyrazoles with methoxymethylene Meldrum's acid derivatives and thermolysis of their pyrazolylaminomethylene derivatives

被引：43

作者：

Quiroga, J ^{[1
]}

Hormaza, A

Insuasty, B

机构：

[1] Univ Valle, Dept Chem, Cali 25360, Colombia

[2] Univ Chile, Dept Quim Organ & Fisicoquim, Santiago, Chile

[3] Univ Chile, CEPEDEQ, Santiago, Chile

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1998年 / 35卷 / 01期

关键词：

D O I：

10.1002/jhet.5570350112

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of pyrazolo[1,5-a]pyrimidin-3-ones 3 was prepared from Meldrum's acid and 5-amino-3-arylpyrazoles 1 by cyclization in nitrobenzene of the corresponding 5-pyrazolylaminomethylene Meldrum's acid derivatives 2. The structure of pyrazolo[1,5-a]pyrimidin-3-ones and their precursors were determined by nmr measurements.

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页码：61 / 64

页数：4

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