Recent progress of carbon dots in targeted bioimaging and cancer

被引:83
作者
Shen, Cheng-Long [1 ,2 ]
Liu, Hang-Rui [3 ]
Lou, Qing [1 ,2 ]
Wang, Feng [3 ]
Liu, Kai-Kai [1 ,2 ]
Dong, Lin [1 ,2 ]
Shan, Chong-Xin [1 ,2 ]
机构
[1] Zhengzhou Univ, Lab Mat Phys, Minist Educ, Zhengzhou 450052, Peoples R China
[2] Zhengzhou Univ, Sch Phys & Microelect, Zhengzhou 450052, Peoples R China
[3] Zhengzhou Univ, Affiliated Hosp 1, Dept Oncol, Zhengzhou 450052, Peoples R China
基金
中国博士后科学基金; 中国国家自然科学基金;
关键词
Carbon dots; targeted bioimaging; cancer therapy; nanotheranostic; SEMICONDUCTING POLYMER NANOPARTICLES; DRUG-DELIVERY; PHOTODYNAMIC THERAPY; ANTICANCER DRUG; ANTIANGIOGENIC THERAPY; MAGNETIC-RESONANCE; TUMOR ANGIOGENESIS; QUANTUM DOTS; IN-VITRO; FLUORESCENT;
D O I
10.7150/thno.70721
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Carbon dots (CDs), as one new class of carbon nanomaterials with various structure and extraordinary physicochemical properties, have attracted tremendous interest for their potential applications in tumor theranostics, especially in targeted bioimaging and therapy. In these areas, CDs and its derivatives have been employed as highly efficient imaging agent for photoluminescence bioimaging of tumors cells. With unique structure, optical and/or dose attention properties, CDs have been harnessed in various nanotheranostic strategies for diverse tumors through integrating with other functional nanoparticles or utilizing their inherent physical properties. Up to now, CDs have been approved as novel biomaterials by their excellent performances in precise targeted bioimaging and therapy for tumors. Herein, the latest progress in the development of CDs in targeted bioimaging and tumor therapy are reviewed. Meanwhile, the challenges and future prospects of the application of CDs in promising nanotheranostic strategies are discussed and proposed.
引用
收藏
页码:2860 / 2893
页数:34
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