3-Boryl-2,1-borazaronaphthalene: Umpolung Reagents for Diversifying Naphthalene Isosteres

被引：7

作者：

Compton, Jordan S. ^{[1
]}

Saeednia, Borna ^{[1
]}

Kelly, Christopher B. ^{[1
]}

Molander, Gary A. ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Roy & Diana Vagelos Labs, 231 South 34th St, Philadelphia, PA 19104 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 83卷 / 16期

关键词：

FIELD-EFFECT TRANSISTORS; BROMINATED 2,1-BORAZARONAPHTHALENES; AZABORINE COMPOUNDS; CHEMISTRY;

D O I：

10.1021/acs.joc.8b01197

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A Pd-catalyzed Miyaura borylation of 3-bromo-2,1-borazaronaphthalenes is reported. This method allows the formation of umpolung reagents for subsequent Pd-mediated cross-coupling. Coupling of this nucleophilic partner with a variety of commercially available aryl- and heteroaryl halides allows facile and rapid diversification of these cores.

引用

页码：9484 / 9491

页数：8

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