Risk factors in the etiology of lung cancer

被引:0
作者
Goron, Monica [1 ]
Milena, Man [1 ]
Bondor, Cosmina [1 ]
Arghir, Oana [1 ]
机构
[1] Spitalul Pneumoftiziol Baia Mare, Cluj Napoca, Romania
来源
RECENT ADVANCES IN CLINICAL MEDICINE | 2010年
关键词
lung cancer; etiology; risk factor; smoking; TISSUE POLYPEPTIDE ANTIGEN; TUMOR-MARKER; CYFRA-21-1; EXPRESSION; FRAGMENT;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The complex plurifactorial determinism of lung cancer demonstrates the need to know the causes and mechanisms of carcinogenesis. We carried out the statistical analysis of 116 patients diagnosed with lung cancer, in the Clinic of Pneumology, Cluj-Napoca, between 1999-2005. We analized the age and the gender of the patients, the origin of the patients, risk factors for lung cancer - LC (especially smoking and toxic environment at work) in correlation with the histological type, their pathological personal history and heredocolateral antecedents with risk of developing lung cancer correlated with the histological type and patients' characteristics, aiming at the existence of a basis of genetic predisposition to cancer in the patients taking part in the study Despite the progress recorded in translating the mechanisms of carcinogenesis and diagnostic imaging, lung cancer cure rates are still low. The key intervention in reducing LC is prophylaxis:quiting smoking
引用
收藏
页码:207 / 212
页数:6
相关论文
共 16 条
[1]   EXPRESSION OF MONOCLONAL ANTIBODY-DEFINED EPITOPES OF KERATIN-19 IN HUMAN-TUMORS AND CULTURED-CELLS [J].
BARTEK, J ;
BARTKOVA, J ;
SCHNEIDER, J ;
TAYLORPAPADIMITRIOU, J ;
KOVARIK, J ;
REJTHAR, A .
EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY, 1986, 22 (12) :1441-1452
[2]   The new World Health Organization classification of lung tumours [J].
Brambilla, E ;
Travis, WD ;
Colby, TV ;
Corrin, B ;
Shimosato, Y .
EUROPEAN RESPIRATORY JOURNAL, 2001, 18 (06) :1059-1068
[3]  
Buccheri G, 1999, LUNG BIOL HEALTH DIS, V124, P435
[4]   PROGNOSTIC VALUE OF THE TISSUE POLYPEPTIDE ANTIGEN IN LUNG-CANCER [J].
BUCCHERI, G ;
FERRIGNO, D .
CHEST, 1992, 101 (05) :1287-1292
[5]   THE TISSUE POLYPEPTIDE ANTIGEN SERUM TEST IN THE PREOPERATIVE EVALUATION OF NONSMALL CELL LUNG-CANCER - DIAGNOSTIC YIELD AND COMPARISON WITH CONVENTIONAL STAGING METHODS [J].
BUCCHERI, G ;
FERRIGNO, D .
CHEST, 1995, 107 (02) :471-476
[6]  
CHIRICUTA I, 1984, BIOL CANC CANC, V1, P205
[7]  
EMILIA C, 2005, BRONHOSCOPIE TEHNICI, P9
[8]  
GHERASIM L, 2002, TRATAT MED INTERNA, V1, P437
[9]   Evaluation of cytokeratin 19 fragment (CYFRA 21-1) as a tumor marker in malignant pleural effusion [J].
Lai, RS ;
Chen, CC ;
Lee, PC ;
Lu, JY .
JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 1999, 29 (09) :421-424
[10]  
MIRON L, 2002, CANCERUL BRONHOPULMO, P103