Development and influence of inhibition in the lateral superior olivary nucleus

被引：83
|
作者：
Sanes, DH
Friauf, E
机构：
[1] NYU, Ctr Neural Sci, New York, NY 10016 USA
[2] Univ Kaiserslautern, FB Biol, Abt Tierphysiol, D-67653 Kaiserslautern, Germany
来源：
HEARING RESEARCH | 2000年 / 147卷 / 1-2期
关键词：
superior olivary complex; glycine; gamma-aminobutyric acid; neurotransmission; dendrite;
D O I：
10.1016/S0378-5955(00)00119-2
中图分类号：
R36 [病理学]; R76 [耳鼻咽喉科学];
学科分类号：
100104 ; 100213 ;
摘要：
While studies of neuronal development and plasticity have focused on excitatory pathways, the inhibitory projection from the MNTB to the LSO provides a favorable model for studies of synaptic inhibition. This review covers recent studies from our laboratories indicating that inhibitory connections are quite dynamic during development, These findings suggest that there are two phases inhibitory transmission. During an initial depolarizing phase is growth and branching of pre- and postsynaptic elements in the LSO. During a second hyperpolarizing phase there is refinement of inhibitory afferent arborizations and the LSO dendrites that they innervate. (C) 2000 Elsevier Science B.V. All rights reserved.
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页码：46 / 58
页数：13
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