Induction Chemotherapy in the Management of Head and Neck Cancer

被引:11
作者
Fury, Matthew G. [1 ,2 ]
Shah, Jatin P. [3 ,4 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Head & Neck Med Oncol Serv, Dept Med, New York, NY 10065 USA
[2] Cornell Univ, Dept Med, Weill Med Coll, New York, NY 10021 USA
[3] Mem Sloan Kettering Canc Ctr, Head & Neck Serv, Dept Surg, New York, NY 10065 USA
[4] Cornell Univ, Dept Surg, Weill Med Coll, New York, NY 10021 USA
关键词
squamous cell carcinoma; head and neck cancer; induction chemotherapy; SQUAMOUS-CELL CARCINOMA; COOPERATIVE-ONCOLOGY-GROUP; LOCALLY ADVANCED HEAD; PHASE-II TRIAL; HUMAN-PAPILLOMAVIRUS; RANDOMIZED-TRIAL; CONCOMITANT RADIOCHEMOTHERAPY; CONCURRENT CHEMORADIOTHERAPY; NEOADJUVANT CHEMOTHERAPY; ORGAN PRESERVATION;
D O I
10.1002/jso.21438
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The strategy of induction chemotherapy prior to planned definitive local therapy for head and neck squamous cell carcinoma has been studied for over 30 years. and appears to have a role in select clinical situations. Here we review landmark studies regarding induction chemotherapy, both in the pre-taxane era and in the current taxane era, and we address some of the unresolved questions regarding the role of induction chemotherapy in head and neck cancer. J. Surg. Oncol. 2010:101:292-298. (C) 2010 Wiley-Liss, Inc.
引用
收藏
页码:292 / 298
页数:7
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