Thrombotic thrombocytopenic purpura in a patient with genetic haemochromatosis, liver cirrhosis and an iron-free focus

被引：1
作者：
Killick, S
Jeffery, S
Otter, M
Rist, C
Bevan, D
机构：
[1] St George Hosp, Sch Med, Div Haematol, Dept Haematol, London SW17 0RE, England
[2] St George Hosp, Sch Med, Dept Med Genet, London SW17 0RE, England
[3] St George Hosp, Sch Med, Dept Histopathol, London SW17 0RE, England
[4] Worthing Hosp, Dept Haematol, Worthing, W Sussex, England
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 1997年 / 99卷 / 04期
关键词：
TTP; haemochromatosis; HFE; Cys282Tyr mutation; hepatic iron-free focus;
D O I：
10.1046/j.1365-2141.1997.4873293.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report a patient with thrombotic thrombocytopenic purpura and genetic haemochromatosis. The patient was shown by the polymerase chain reaction to be homozygous for the Cys282Tyr mutation of the HFE gene. Liver biopsy showed micronodular cirrhosis and the presence of an iron-free focus which was thought to be pre-neoplastic.
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页码：839 / 841
页数：3
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