The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention

被引:1018
作者
Holick, Michael F. [1 ]
机构
[1] Boston Univ, Med Ctr, Dept Med, Endocrinol Nutr & Diabet, Boston, MA 02118 USA
关键词
Vitamin D deficiency; Vitamin D insufficiency; Sunlight; Rickets; Vitamin D-2; Vitamin D-3; 25-hydroxyvitamin D; Vitamin D toxicity; 25-HYDROXYVITAMIN D CONCENTRATIONS; HYPOVITAMINOSIS-D; D SUPPLEMENTATION; SUN EXPOSURE; CARDIOVASCULAR-DISEASE; ULTRAVIOLET-RADIATION; HIGH PREVALENCE; HEALTHY-ADULTS; D INTOXICATION; RISK-FACTOR;
D O I
10.1007/s11154-017-9424-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Vitamin D deficiency and insufficiency is a global health issue that afflicts more than one billion children and adults worldwide. The consequences of vitamin D deficiency cannot be under estimated. There has been an association of vitamin D deficiency with a myriad of acute and chronic illnesses including preeclampsia, childhood dental caries, periodontitis, autoimmune disorders, infectious diseases, cardiovascular disease, deadly cancers, type 2 diabetes and neurological disorders. This review is to put into perspective the controversy surrounding the definition for vitamin D deficiency and insufficiency as well as providing guidance for how to treat and prevent vitamin D deficiency.
引用
收藏
页码:153 / 165
页数:13
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