Dysfunction in attentional processing in patients with Parkinson's disease and visual hallucinations

被引：21

作者：

Hall, Julie M. ^{[1
,2
]}

O'Callaghan, Claire ^{[1
,3
]}

Shine, James M. ^{[1
,4
,5
]}

Muller, Alana J. ^{[1
]}

Phillips, Joseph R. ^{[2
]}

Walton, Courtney C. ^{[1
]}

Lewis, Simon J. G. ^{[1
]}

Moustafa, Ahmed A. ^{[2
,6
]}

机构：

[1] Univ Sydney, Parkinsons Dis Res Clin, Brain & Mind Ctr, Sydney, NSW 2006, Australia

[2] Univ Western Sydney, Sch Social Sci & Psychol, Sydney, NSW, Australia

[3] Univ Cambridge, Behav & Clin Neurosci Inst, Cambridge, England

[4] Stanford Univ, Sch Psychol, Palo Alto, CA 94304 USA

[5] Univ New S Wales, Neurosci Res Australia, Sydney, NSW, Australia

[6] Univ Western Sydney, MARCS Inst Brain Behav & Dev, Sydney, NSW, Australia

来源：

JOURNAL OF NEURAL TRANSMISSION | 2016年 / 123卷 / 05期

基金：

英国医学研究理事会; 澳大利亚国家健康与医学研究理事会;

关键词：

Parkinson's disease; Visual hallucinations; Attentional network test; Dorsal attentional network; NETWORK; DISORDERS; ANATOMY; BRAIN;

D O I：

10.1007/s00702-016-1528-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Mechanistic insights into visual hallucinations (VH) in Parkinson's disease (PD) have suggested a role for impaired attentional processes. The current study tested 25 PD patients with and 28 PD patients without VH on the attentional network test. Hallucinators had significantly lower accuracy rates compared to non-hallucinators, but no differences were found in reaction times. This suggests that hallucinators show deficits in attentional processes and conflict monitoring. Our findings provide novel behavioural insights that dovetail with current neurobiological frameworks of VH.

引用

页码：503 / 507

页数：5

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