Dysfunction in attentional processing in patients with Parkinson's disease and visual hallucinations

被引：21

作者：

Hall, Julie M. ^{[1
,2
]}

O'Callaghan, Claire ^{[1
,3
]}

Shine, James M. ^{[1
,4
,5
]}

Muller, Alana J. ^{[1
]}

Phillips, Joseph R. ^{[2
]}

Walton, Courtney C. ^{[1
]}

Lewis, Simon J. G. ^{[1
]}

Moustafa, Ahmed A. ^{[2
,6
]}

机构：

[1] Univ Sydney, Parkinsons Dis Res Clin, Brain & Mind Ctr, Sydney, NSW 2006, Australia

[2] Univ Western Sydney, Sch Social Sci & Psychol, Sydney, NSW, Australia

[3] Univ Cambridge, Behav & Clin Neurosci Inst, Cambridge, England

[4] Stanford Univ, Sch Psychol, Palo Alto, CA 94304 USA

[5] Univ New S Wales, Neurosci Res Australia, Sydney, NSW, Australia

[6] Univ Western Sydney, MARCS Inst Brain Behav & Dev, Sydney, NSW, Australia

来源：

JOURNAL OF NEURAL TRANSMISSION | 2016年 / 123卷 / 05期

基金：

英国医学研究理事会; 澳大利亚国家健康与医学研究理事会;

关键词：

Parkinson's disease; Visual hallucinations; Attentional network test; Dorsal attentional network; NETWORK; DISORDERS; ANATOMY; BRAIN;

D O I：

10.1007/s00702-016-1528-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Mechanistic insights into visual hallucinations (VH) in Parkinson's disease (PD) have suggested a role for impaired attentional processes. The current study tested 25 PD patients with and 28 PD patients without VH on the attentional network test. Hallucinators had significantly lower accuracy rates compared to non-hallucinators, but no differences were found in reaction times. This suggests that hallucinators show deficits in attentional processes and conflict monitoring. Our findings provide novel behavioural insights that dovetail with current neurobiological frameworks of VH.

引用

页码：503 / 507

页数：5

共 23 条

[1] AN INVENTORY FOR MEASURING DEPRESSION
BECK, AT
ERBAUGH, J
WARD, CH
MOCK, J
MENDELSOHN, M
[J]. ARCHIVES OF GENERAL PSYCHIATRY, 1961, 4 (06) : 561 - &
[2] The brain's default network - Anatomy, function, and relevance to disease
Buckner, Randy L.
Andrews-Hanna, Jessica R.
Schacter, Daniel L.
[J]. YEAR IN COGNITIVE NEUROSCIENCE 2008, 2008, 1124 : 1 - 38
[3] EFFECTS OF NOISE LETTERS UPON IDENTIFICATION OF A TARGET LETTER IN A NONSEARCH TASK
ERIKSEN, BA
ERIKSEN, CW
[J]. PERCEPTION & PSYCHOPHYSICS, 1974, 16 (01): : 143 - 149
[4] Testing the efficiency and independence of attentional networks
Fan, J
McCandliss, BD
Sommer, T
Raz, A
Posner, MI
[J]. JOURNAL OF COGNITIVE NEUROSCIENCE, 2002, 14 (03) : 340 - 347
[5] FOLSTEIN MF, 1983, ARCH GEN PSYCHIAT, V40, P812
[6] Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS): A new scale for the evaluation of Parkinson's disease
Goetz, C. G.
[J]. REVUE NEUROLOGIQUE, 2010, 166 (01) : 1 - 4
[7] Prospective longitudinal assessment of hallucinations in Parkinson's disease
Goetz, CG
Leurgans, S
Pappert, EJ
Raman, R
Stemer, AB
[J]. NEUROLOGY, 2001, 57 (11) : 2078 - 2082
[8] Hallucinations and sleep disorders in PD Ten-year prospective longitudinal study
Goetz, Christopher G.
Ouyang, Bichun
Negron, Alice
Stebbins, Glenn T.
[J]. NEUROLOGY, 2010, 75 (20) : 1773 - 1779
[9] Visuoperceptive region atrophy independent of cognitive status in patients with Parkinson's disease with hallucinations
Goldman, Jennifer G.
Stebbins, Glenn T.
Dinh, Vy
Bernard, Bryan
Merkitch, Doug
deToledo-Morrell, Leyla
Goetz, Christopher G.
[J]. BRAIN, 2014, 137 : 849 - 859
[10] The Sydney multicenter study of Parkinson's disease: The inevitability of dementia at 20 years
Hely, Mariese A.
Reid, Wayne G. J.
Adena, Michael A.
Halliday, Glenda A.
Morris, John G. L.
[J]. MOVEMENT DISORDERS, 2008, 23 (06) : 837 - 844

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