Mesenchymal Stem Cells and Tooth Engineering

被引:68
作者
Peng, Li [1 ]
Ye, Ling [1 ]
Zhou, Xue-dong [1 ]
机构
[1] Sichuan Univ, State Key Lab Oral Dis, W China Coll Stomatol, Chengdu 610041, Peoples R China
关键词
mesenchymal stem cell; tooth engineering; dental pulp stem cell; HUMAN PERIODONTAL-LIGAMENT; DENTAL FOLLICLE CELLS; NONCOLLAGENOUS PROTEINS DNCPS; ODONTOGENIC EPITHELIAL-CELLS; EXFOLIATED DECIDUOUS TEETH; IN-VIVO; PROGENITOR CELLS; ADIPOSE-TISSUE; STROMAL CELLS; PULP;
D O I
10.4248/ijos.08032
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Tooth loss compromises human oral health. Although several prosthetic methods, such as artificial denture and dental implants, are clinical therapies to tooth loss problems, they are thought to have safety and usage time issues. Recently, tooth tissue engineering has attracted more and more attention. Stem cell based tissue engineering is thought to be a promising way to replace the missing tooth. Mesenchymal stem cells (MSCs) are multipotent stem cells which can differentiate into a variety of cell types. The potential MSCs for tooth regeneration mainly include stem cells from human exfoliated deciduous teeth (SHEDs), adult dental pulp stem cells (DPSCs), stem cells from the apical part of the papilla (SCAPs), stem cells from the dental follicle (DFSCs), periodontal ligament stem cells (PDLSCs) and bone marrow derived mesenchymal stem cells (BMSCs). This review outlines the recent progress in the mesenchymal stem cells used in tooth regeneration.
引用
收藏
页码:6 / 12
页数:7
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