Synthesis and Antimicrobial Activity of Novel Ag-N-Heterocyclic Carbene Complexes

被引：54

作者：

Ozdemir, Ilknur ^{[1
]}

Ozcan, Emine Ozge ^{[1
]}

Gunal, Selami ^{[2
]}

Gurbuz, Nevin ^{[1
]}

机构：

[1] Inonu Univ, Fac Sci & Art, Dept Chem, TR-44280 Malatya, Turkey

[2] Inonu Univ, Fac Med, Dept Microbiol, TR-44280 Malatya, Turkey

来源：

MOLECULES | 2010年 / 15卷 / 04期

关键词：

N-Heterocyclic carbene; silver complexes; antimicrobial activity; imidazolidin-2-ylidene; IN-VITRO; STRUCTURAL-CHARACTERIZATION; SILVER COMPLEXES; POLYMERS; ACID; DINUCLEAR; LIGANDS;

D O I：

10.3390/molecules15042499

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A series of imidazolidinium ligand precursors are metallated with Ag2O to give silver(I) N-heterocyclic carbene complexes. All compounds were fully characterized by elemental analyses, H-1-NMR, C-13-NMR and IR spectroscopy techniques. All compounds studied in this work were screened for their in vitro antimicrobial activities against the standard strains: Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853) and the fungi Candida albicans and Candida tropicalis. The new imidazolidin-2-ylidene silver complexes have been found to display effective antimicrobial activity against a series of bacteria and fungi.

引用

页码：2499 / 2508

页数：10

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