Synthesis of New [1,2,4]Triazolo[1,5-a]pyrimidine Derivatives: Reactivity of 3-Amino[1,2,4]triazole towards Enaminonitriles and Enaminones

被引：13

作者：

Alnajjar, Abdulaziz ^{[1
]}

Abdelkhalik, Mervat Mohammed ^{[1
]}

Raslan, Mohamed Abdelmonem ^{[2
]}

Ibraheem, Solwan Maher ^{[2
]}

Sadek, Kamal Usef ^{[3
]}

机构：

[1] Publ Author Appl Educ & Training, Appl Sci Dept, Coll Technol Studies, POB 42325, Safat 70654, Kuwait

[2] Aswan Univ, Chem Dept, Fac Sci, Aswan 81528, Egypt

[3] Menia Univ, Chem Dept, Fac Sci, Al Minya 61519, Egypt

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2018年 / 55卷 / 07期

关键词：

AGENTS;

D O I：

10.1002/jhet.3222

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A diversity of new 7-substituted[1,2,4]triazolo[1,5-a]pyrimidine and 6-substituted[1,2,4]triazolo[1,5-a]pyrimidine-7-amine derivatives has been synthesized via reaction of 3-amino-[1,2,4]triazole with enaminonitriles and enaminones. The regio orientation and the structure of the products were confirmed by spectral and analytical data and synthesis via an alternative route. The procedure proved to be simple, efficient, and high yielding, and diversities of [1,2,4]triazolo[1,5-a]pyrimidines were obtained.

引用

页码：1804 / 1808

页数：5

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