Successful golimumab therapy in four patients with refractory Takayasu's arteritis

被引:6
作者
Suematsu, Rie [1 ]
Tashiro, Satoko [1 ]
Ono, Nobuyuki [1 ]
Koarada, Syuichi [1 ]
Ohta, Akihide [2 ]
Tada, Yoshifumi [1 ]
机构
[1] Saga Univ, Sch Med, Dept Rheumatol, 5-1-1 Nabeshima, Saga 8498501, Japan
[2] Saga Univ, Sch Med, Dept Adult & Gerontol Nursing, Saga, Japan
关键词
Biologics; Golimumab; Takayasu's arteritis; ACTIVE RHEUMATOID-ARTHRITIS; LARGE-VESSEL VASCULITIS; JAPANESE PATIENTS; METHOTREXATE; TOCILIZUMAB; MONOTHERAPY; MULTICENTER; MANAGEMENT; RESISTANT; SERIES;
D O I
10.3109/14397595.2015.1134393
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Recent studies suggested that anti-TNF- biological therapies are effective in treating Takayasu's arteritis (TA) refractory to conventional immunosuppressive therapy. However, the efficacy of golimumab (GLM) for TA therapy is unknown. We report four women with TA who were successfully treated with GLM. GLM was prescribed as induction therapy for three patients and as maintenance therapy for one patient. GLM showed therapeutic value and might be useful, together with other anti-TNF- agents, in treating TA.
引用
收藏
页码:712 / 715
页数:4
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