snakePipes: facilitating flexible, scalable and integrative epigenomic analysis

被引:109
作者
Bhardwaj, Vivek [1 ,2 ]
Heyne, Steffen [1 ]
Sikora, Katarzyna [1 ]
Rabbani, Leily [1 ]
Rauer, Michael [1 ]
Kilpert, Fabian [3 ,4 ]
Richter, Andreas S. [5 ]
Ryan, Devon P. [1 ]
Manke, Thomas [1 ]
机构
[1] Max Planck Inst Immunobiol & Epigenet, D-79108 Freiburg, Germany
[2] Univ Freiburg, Fac Biol, D-79104 Freiburg, Germany
[3] Univ Lubeck, Inst Neurogenet, D-23562 Lubeck, Germany
[4] Univ Lubeck, Inst Cardiogenet, D-23562 Lubeck, Germany
[5] Genedata AG, CH-4053 Basel, Switzerland
关键词
D O I
10.1093/bioinformatics/btz436
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The Summary: Due to the rapidly increasing scale and diversity of epigenomic data, modular and scalable analysis workflows are of wide interest. Here we present snakePipes, a workflow package for processing and downstream analysis of data from common epigenomic assays: ChIP-seq, RNA-seq, Bisulfite-seq, ATAC-seq, Hi-C and single-cell RNA-seq. snakePipes enables users to assemble variants of each workflow and to easily install and upgrade the underlying tools, via its simple command-line wrappers and yaml files.
引用
收藏
页码:4757 / 4759
页数:3
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