Crohn's disease exclusion diet in children with Crohn's disease: a case series

被引：20

作者：

Scarallo, Luca ^{[1
]}

Banci, Elena ^{[2
]}

Pierattini, Valentina ^{[2
]}

Lionetti, Paolo ^{[1
,3
]}

机构：

[1] Meyer Childrens Hosp, Gastroenterol & Nutr Unit, I-50139 Florence, Italy

[2] Meyer Childrens Hosp, Dietet Unit, Florence, Italy

[3] Univ Florence, Dept Neurosci Psychol Pharmacol & Child Hlth NEUR, Florence, Italy

来源：

CURRENT MEDICAL RESEARCH AND OPINION | 2021年 / 37卷 / 07期

关键词：

Adherence; Crohn’ s disease (CD); s disease exclusion diet (CDED); partial enteral nutrition (PEN); remission; tolerance; INFLAMMATORY-BOWEL-DISEASE;

D O I：

10.1080/03007995.2021.1920901

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Exclusive enteral nutrition (EEN) represents an established, evidence-based dietary therapy used in Crohn's disease (CD); although successful, EEN is extremely restrictive with limited acceptability and prolonged use. The Crohn's disease exclusion diet (CDED) is a new, sustainable and patient-friendly dietary therapy used for the management of pediatric CD. CDED is designed to reduce exposure to dietary components hypothesized to negatively affect the microbiome, intestinal barrier and immunity. By focusing on five clinical cases, this article illustrates the benefits of using CDED as mono- or co-therapy with partial enteral nutrition in children with mild to moderate CD. CDED combined with partial enteral nutrition is a safe and effective therapeutic option for both induction and maintenance therapy in children with mild to moderate CD. It ensures sustained remission and can induce mucosal healing in children with mild to moderate Crohn's disease.

引用

页码：1115 / 1120

页数：6

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