Screening of anti-diarrhoeal profile of some plant extracts of a specific region of West Bengal, India

被引:122
作者
Mukherjee, PK [1 ]
Saha, K [1 ]
Murugesan, T [1 ]
Mandal, SC [1 ]
Pal, M [1 ]
Saha, BP [1 ]
机构
[1] Jadavpur Univ, Fac Engn & Technol, Dept Pharmaceut Technol, Calcutta 700032, W Bengal, India
关键词
Ficus bengalensis hanging roots; Ficus racemosa bark; Eugenia jambolana bark; Leucas lavandulaefolia aerial parts; anti-diarrhoeal;
D O I
10.1016/S0378-8741(97)00130-X
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Ethanol extract of four different plants of the Khatra region of the Bankura district of West Bengal, India were evaluated for anti-diarrhoeal activity against different experimental models of diarrhoea in rats. The extracts of Ficus bengalensis Linn. (hanging roots), Eugenia jambolana Lam. (bark), Ficus racemosa Linn. (bark) and Leucas lavandulaefolia Rees (aerial parts) showed significant inhibitory activity against castor oil induced diarrhoea and PGE(2) induced enteropooling in rats. These extracts also showed a significant reduction in gastrointestinal motility in charcoal meal tests in rats. The results obtained establish the efficacy of all these plant materials as anti-diarrhoeal agents. (C) 1998 Elsevier Science Ireland Ltd.
引用
收藏
页码:85 / 89
页数:5
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