Fabrication and biocompatibility investigation of TiO2 films on the polymer substrates obtained via a novel and versatile route

被引：75
作者：
Ou, Junfei [1 ,2 ]
Wang, Jinqing [1 ]
Zhang, Dong [3 ]
Zhang, Puliang [3 ]
Liu, Sheng [1 ,2 ]
Yan, Penghua [1 ]
Liu, Bin [3 ]
Yang, Shengrong [1 ]
机构：
[1] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China
[2] Chinese Acad Sci, Grad Univ, Beijing 100080, Peoples R China
[3] Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China
来源：
COLLOIDS AND SURFACES B-BIOINTERFACES | 2010年 / 76卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Implanted polymer materials; Polydopamine coating; TiO2; films; Biocompatibility; OXIDE THIN-FILMS; SURFACE MODIFICATION; DEPOSITION; ADHESION; GROWTH; GLASS;
D O I：
10.1016/j.colsurfb.2009.10.024
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Titanium oxide (TiO2) films were successfully deposited onto the polymer Substrates of polytetrafluoroethylene (PTFE), polyethylene (PE), and polyethylene terephthalate (PET), which were pre-modified with polyclopamine coating (polydopamine and its coating are coded as PDA and PDAc, respectively), by a simple liquid phase deposition (LPD) process. The morphology and chemical state of the obtained TiO2 films were characterized by field emission scanning electron microscope (FE-SEM) and X-ray photoelectron spectroscopy (XPS), respectively. Subsequently, the biocompatibility of the samples was investigated by 3-(4,5-dimethyldiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) colorimetric assay and acridine orange staining of MC-3T3 osteoblast cells. and the results demonstrated that the fabricated TiO2 films could markedly improve the in vitro cytocompatibility. So, the presented route is anticipated to be a promising Surface modification methodology to improve the practical outcome of the implanted materials for its versatility and validity. (C) 2009 Elsevier B.V. All rights reserved.
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收藏
页码：123 / 127
页数：5
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