Palladium-catalyzed Decarbonylative Alkynylation of Aromatic Esters

被引：51
|
作者：
Okita, Toshimasa [1 ]
Kumazawa, Kazushi [2 ,3 ]
Takise, Ryosuke [2 ,3 ]
Muto, Kei [1 ]
Itami, Kenichiro [2 ,3 ,4 ]
Yamaguchi, Junichiro [1 ]
机构：
[1] Waseda Univ, Dept Appl Chem, Shinjuku Ku, 3-4-1 Ohkubo, Tokyo 1698555, Japan
[2] Nagoya Univ, Inst Transformat Biomol WPI ITbM, Chikusa Ku, Nagoya, Aichi 4648602, Japan
[3] Nagoya Univ, Grad Sch Sci, Chikusa Ku, Nagoya, Aichi 4648602, Japan
[4] Nagoya Univ, JST ERATO, Itami Mol Nanocarbon Project, Chikusa Ku, Nagoya, Aichi 4648602, Japan
来源：
CHEMISTRY LETTERS | 2017年 / 46卷 / 02期
关键词：
Decarbonylative reaction; Palladium; Alkyne; HAGIHARA COUPLING REACTIONS; ARYL IODIDES; NICKEL; ALKYNYLSILANES; CHLORIDES; AZOLES; AMIDES; CHEMOSELECTIVITY; OLEFINATION; SILYLATION;
D O I：
10.1246/cl.161001
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.
引用
收藏
页码：218 / 220
页数：3
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