Palladium-catalyzed Decarbonylative Alkynylation of Aromatic Esters

被引：52

作者：

Okita, Toshimasa ^{[1
]}

Kumazawa, Kazushi ^{[2
,3
]}

Takise, Ryosuke ^{[2
,3
]}

Muto, Kei ^{[1
]}

Itami, Kenichiro ^{[2
,3
,4
]}

Yamaguchi, Junichiro ^{[1
]}

机构：

[1] Waseda Univ, Dept Appl Chem, Shinjuku Ku, 3-4-1 Ohkubo, Tokyo 1698555, Japan

[2] Nagoya Univ, Inst Transformat Biomol WPI ITbM, Chikusa Ku, Nagoya, Aichi 4648602, Japan

[3] Nagoya Univ, Grad Sch Sci, Chikusa Ku, Nagoya, Aichi 4648602, Japan

[4] Nagoya Univ, JST ERATO, Itami Mol Nanocarbon Project, Chikusa Ku, Nagoya, Aichi 4648602, Japan

来源：

CHEMISTRY LETTERS | 2017年 / 46卷 / 02期

关键词：

Decarbonylative reaction; Palladium; Alkyne; HAGIHARA COUPLING REACTIONS; ARYL IODIDES; NICKEL; ALKYNYLSILANES; CHLORIDES; AZOLES; AMIDES; CHEMOSELECTIVITY; OLEFINATION; SILYLATION;

D O I：

10.1246/cl.161001

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.

引用

页码：218 / 220

页数：3

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