The DOSY experiment provides insights into the protegrin-lipid interaction

被引：8

作者：

Malliavin, TE ^{[1
]}

Louis, V ^{[1
]}

Delsuc, MA ^{[1
]}

机构：

[1] Fac Pharm Montpellier, INSERM, CNRS, Ctr Biochim Struct,UMR 9955,U414, F-34000 Montpellier, France

来源：

JOURNAL DE CHIMIE PHYSIQUE ET DE PHYSICO-CHIMIE BIOLOGIQUE | 1998年 / 95卷 / 02期

关键词：

DOSY; micelle; protegrin; MaxEnt;

D O I：

10.1051/jcp:1998118

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The measure of translational diffusion using PFG NMR has known a renewal of interest with the development of the DOSY experiments. The extraction of diffusion coefficients from these experiments requires an inverse Laplace transform. We present here the use of the Maximum Entropy technique to perform this transform, and an application of this method to investigate the interaction protegrin-lipid. We show that the analysis by DOSY experiments permits to determine some of the interaction features.

引用

页码：178 / 186

页数：9

共 19 条

[1] ASSOCIATION OF BIOMOLECULAR SYSTEMS VIA PULSED-FIELD GRADIENT NMR SELF-DIFFUSION MEASUREMENTS [J].