Adult heart transplant: indications and outcomes

被引:133
作者
Alraies, M. Chadi [1 ]
Eckman, Peter [1 ]
机构
[1] Univ Minnesota, Dept Med, Div Cardiovasc Med, Minneapolis, MN 55455 USA
关键词
Heart transplant; indications; outcomes; VENTRICULAR ASSIST DEVICE; ORGAN-SHARING-DATABASE; ASSOCIATION TASK-FORCE; UNITED-NETWORK; CARDIAC TRANSPLANTATION; INTERNATIONAL SOCIETY; VENTILATORY EFFICIENCY; AMBULATORY PATIENTS; OF-CARDIOLOGY; FAILURE-ASSOCIATION;
D O I
10.3978/j.issn.2072-1439.2014.06.44
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Cardiac transplantation is the treatment of choice for many patients with end-stage heart failure (HF) who remain symptomatic despite optimal medical therapy. For carefully selected patients, heart transplantation offers markedly improved survival and quality of life. Risk stratification of the large group of patients with end-stage HF is essential for identifying patients who are most likely to benefit, particularly as the number of suitable donors is insufficient to meet demand. The indications for heart transplant and review components of the pre-transplant evaluation, including the role for exercise testing and risk scores such as the Heart Failure Survival Score (HFSS) and Seattle Heart Failure Model (SHFM) are summarized. Common contraindications are also discussed. Outcomes, including survival and common complications such as coronary allograft vasculopathy are reviewed.
引用
收藏
页码:1120 / 1128
页数:9
相关论文
共 52 条
[31]   Use of a continuous-flow device in patients awaiting heart transplantation [J].
Miller, Leslie W. ;
Pagani, Francis D. ;
Russell, Stuart D. ;
John, Ranjit ;
Boyle, Andrew J. ;
Aaronson, Keith D. ;
Conte, John V. ;
Naka, Yoshifumi ;
Mancini, Donna ;
Delgado, Reynolds M. ;
MacGillivray, Thomas E. ;
Farrar, David J. ;
Frazier, O. H. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (09) :885-896
[32]   Stable patients on left ventricular assist device support have a disproportionate advantage: Time to re-evaluate the current UNOS policy [J].
Moazami, Nader ;
Sun, Benjamin ;
Feldman, David .
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2011, 30 (09) :971-974
[33]   Prediction of mode of death in heart failure the seattle heart failure model [J].
Mozaffarian, Dariush ;
Anker, Stefan D. ;
Anand, Inder ;
Linker, David T. ;
Sullivan, Mark D. ;
Cleland, John G. F. ;
Carson, Peter E. ;
Maggioni, Aldo P. ;
Mann, Douglas L. ;
Pitt, Bertram ;
Poole-Wilson, Philip A. ;
Levy, Wayne C. .
CIRCULATION, 2007, 116 (04) :392-398
[34]   Peak oxygen consumption as a predictor of death in patients with heart failure receiving β-blockers [J].
O'Neill, JO ;
Young, JB ;
Pothier, CE ;
Lauer, MS .
CIRCULATION, 2005, 111 (18) :2313-2318
[35]   Chronic renal failure after transplantation of a nonrenal organ [J].
Ojo, AO ;
Held, PJ ;
Port, FK ;
Wolfe, RA ;
Leichtman, AB ;
Young, EW ;
Arndorfer, J ;
Christensen, L ;
Merion, RM .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (10) :931-940
[36]  
Organ procurement and transplantation network (OPTN), ORG DISTR ALL HEARTS
[37]   Heart Disease and Stroke Statistics-2011 Update A Report From the American Heart Association [J].
Roger, Veronique L. ;
Go, Alan S. ;
Lloyd-Jones, Donald M. ;
Adams, Robert J. ;
Berry, Jarett D. ;
Brown, Todd M. ;
Camethon, Mercedes R. ;
Dai, Shifan ;
de Simone, Giovanni ;
Ford, Earl S. ;
Fox, Caroline S. ;
Fullerton, Heather J. ;
Gillespie, Cathleen ;
Greenlund, Kurt J. ;
Hailpem, Susan M. ;
Heit, John A. ;
Ho, P. Michael ;
Howard, Virginia J. ;
Kissela, Brett M. ;
Kittner, Steven J. ;
Lackland, Daniel T. ;
Lichtman, Judith H. ;
Lisabeth, Lynda D. ;
Makuc, Diane M. ;
Marcus, Gregory M. ;
Marelli, Ariane ;
Matchar, David B. ;
McDermott, Mary M. ;
Meigs, James B. ;
Moy, Claudia S. ;
Mozaffarian, Dariush ;
Mussolino, Michael E. ;
Nichol, Graham ;
Paynter, Nina P. ;
Rosamond, Wayne D. ;
Sorlie, Paul D. ;
Stafford, Randall S. ;
Turan, Tanya N. ;
Turner, Melanie B. ;
Wong, Nathan D. ;
Wylie-Rosett, Judith .
CIRCULATION, 2011, 123 (04) :E18-E209
[38]   Long-term use of a left ventricular assist device for end-stage heart failure [J].
Rose, EA ;
Gelijns, AC ;
Moskowitz, AJ ;
Heitjan, DF ;
Stevenson, LW ;
Dembitsky, W ;
Long, JW ;
Ascheim, DD ;
Tierney, AR ;
Levitan, RG ;
Watson, JT ;
Meier, P .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (20) :1435-1443
[39]   Survival in Elderly Patients Supported With Continuous Flow Left Ventricular Assist Device as Bridge to Transplantation or Destination Therapy [J].
Rosenbaum, Andrew N. ;
John, Ranjit ;
Liao, Kenneth K. ;
Adatya, Sirtaz ;
Colvin-Adams, Monica M. ;
Pritzker, Marc ;
Eckman, Peter M. .
JOURNAL OF CARDIAC FAILURE, 2014, 20 (03) :161-167
[40]   Survival after heart transplantation is not diminished among recipients with uncomplicated diabetes Mellitus - An analysis of the United Network of Organ Sharing Database [J].
Russo, Mark J. ;
Chen, Jonathan M. ;
Hong, Kimberly N. ;
Stewart, Allan S. ;
Ascheim, Deborah D. ;
Argenziano, Michael ;
Mancini, Donna M. ;
Oz, Mehmet C. ;
Naka, Yoshifumi .
CIRCULATION, 2006, 114 (21) :2280-2287