Polihexanide: A Safe and Highly Effective Biocide

被引：99

作者：

Kaehn, K. ^{[1
]}

机构：

[1] K2 Hyg Dienstleistungen, DE-67431 Aschaffenburg, Germany

来源：

SKIN PHARMACOLOGY AND PHYSIOLOGY | 2010年 / 23卷

关键词：

Polihexanide; chemical characteristics; Biocide; Antiseptic; Wounds; POLYHEXAMETHYLENE BIGUANIDE PHMB; IN-VITRO SUSCEPTIBILITY; ESCHERICHIA-COLI; PHOSPHOLIPID-MEMBRANES; ACANTHAMOEBA-KERATITIS; BACTERIAL; WOUNDS; MODEL; CHLORHEXIDINE; DEFENSINS;

D O I：

10.1159/000318237

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Polihexanide is a broad-spectrum antiseptic with excellent tolerance and a low-risk profile. The physicochemical action on the bacterial envelope prevents or impedes the development of resistant bacterial strains. Thus, polihexanide is particularly suitable and useful in the struggle against multidrug-resistant bacteria. The ecological database is still incomplete. There is some evidence that biodegradation requires adsorption to inert surfaces and that only a small number of bacterial species are capable of utilizing polihexanide. Copyright (C) 2010 S. Karger AG, Basel

引用

页码：7 / 16

页数：10

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