Evolution and function of ubiquitin-like protein-conjugation systems

被引：342

作者：

Hochstrasser, M ^{[1
]}

机构：

[1] Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA

来源：

NATURE CELL BIOLOGY | 2000年 / 2卷 / 08期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/35019643

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Ubiquitin functions by covalently modifying other proteins. In the past few years, a surprising number of other proteins have been identified that, despite often being only slightly similar to ubiquitin, can also be attached to proteins. Newly discovered parallels between the activation of ubiquitin and the biosynthesis of certain enzyme cofactors now hint at the possible evolutionary origins of the ubiquitin system.

引用

页码：E153 / E157

页数：5

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