Impact of oncogenes and tumor suppressor genes on deregulation of hemostasis and angiogenesis in cancer

被引：51
作者：
Rak, J [1 ]
Klement, G
机构：
[1] McMaster Univ, Hamilton Civ Hosp, Res Ctr, Hamilton, ON L8V 1C3, Canada
[2] Univ Toronto, Sunnybrook & Womens Coll, Hlth Sci Ctr, Toronto, ON, Canada
来源：
CANCER AND METASTASIS REVIEWS | 2000年 / 19卷 / 1-2期
关键词：
oncogenes; angiogenesis; tumor progression; coagulation; tissue factor; cancer;
D O I：
10.1023/A:1026516920119
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We postulate that oncogenes and tumor suppressor genes may influence tumor angiogenesis not only directly (e.g. by upregulating vascular endothelial growth factor) but also through their impact on expression (and/or function) of tissue factor and other elements of the hemostatic system.
引用
收藏
页码：93 / 96
页数：4
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