Oxazolidin-2-one as Efficient Ligand for the Copper-Catalyzed N-Arylation of Pyrrole, Imidazole and Indole

被引：9

作者：

Ma, Hengchang ^{[1
]}

Wu, Shang ^{[1
]}

Sun, Qiangsheng ^{[1
]}

Lei, Ziqiang ^{[1
]}

机构：

[1] NW Normal Univ, Key Lab Polymer Mat Gansu Prov, Key Lab Ecoenvironm Related Polymer Mat, Coll Chem & Chem Engn,Minist Educ, Lanzhou 730070, Peoples R China

来源：

LETTERS IN ORGANIC CHEMISTRY | 2010年 / 7卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Copper; coupling; catalysis; ligands; arylations; NITROGEN-CONTAINING HETEROCYCLES; ARYL HALIDES; COUPLING REACTION; HIGHLY EFFICIENT; C-N; ESTROGEN-RECEPTOR; EXCELLENT LIGAND; BOND FORMATION; AMINO-ACIDS; AMIDATION;

D O I：

10.2174/157017810791112496

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxazolidin-2-one was found to be a facile ligand for the N-arylation of pyrrole, indole, and imidazole with aryl and heteroaryl iodides, bromides, and chlorides by applying CuI as catalyst. The easy preparation, commercial availability, lower molecular weight, and broad substrate applicability, as well as substituent compatibility of this catalysis system render oxazolidin-2-one great advantages over the Cu-catalyzed methods that have already been utilized in a number of applications.

引用

页码：212 / 218

页数：7

共 44 条

[1] 4,7-Dimethoxy-1,10-phenanthroline:: An excellent ligand for the Cu-catalyzed N-arylation of imidazoles [J].