New steroidal alkaloids from Sarcococca saligna

被引：19

作者：

Rahman, A ^{[1
]}

Choudhary, MI ^{[1
]}

Khan, MR ^{[1
]}

Anjum, S ^{[1
]}

Farooq, A ^{[1
]}

Iqbal, MZ ^{[1
]}

机构：

[1] Univ Karachi, Natl Nematol Res Ctr, Int Ctr Chem Sci, Karachi 75270, Pakistan

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 10期

关键词：

D O I：

10.1021/np990108w

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Five new pregnane-type steroidal alkaloids (1-5) have been isolated from Sarcococca saligna. A combination of UV, IR, MS, and 1D and 2D NMR spectroscopic studies established their structures as salignarine A [(20S);2 beta -hydroxy-4 beta -acetoxy-5 alpha ,6 alpha -epoxy-20-(dimethylamino)-3 beta-(tigloylamino)pregnane] (1), salignarine B [(20S)-2 beta -hydroxy-20-(dimethylamino)-3 beta-(tigloylamino)-pregn-5-ene] (2), salignarine C [(20S)-2 beta -hydroxy-20-(dimethylamino)-3 beta-(senecioylamino)-pregn-5-ene] (3), salignarine D [(20S)-20- dimethylamino)-3 beta-(senecioylamino)-5 alpha -pregn-16-ene] (4), and salignarine E [(20S)-20-(dimethlyamino-3 beta-(tigloylamino)-pregn-4-ene] (5), respectively.

引用

页码：1364 / 1368

页数：5

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