The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot

被引：10

作者：

Dremin, Victor V. ^{[1
]}

Sidorov, Viktor V. ^{[2
]}

Krupatkin, Alexander I. ^{[3
]}

Galstyan, Gagik R. ^{[4
]}

Novikova, Irina N. ^{[1
]}

Zherebtsova, Angelina I. ^{[1
]}

Zherebtsov, Evgeny A. ^{[1
]}

Dunaev, Andrey V. ^{[1
]}

Abdulvapova, Zera N. ^{[4
]}

Litvinova, Karina S. ^{[5
]}

Rafailov, Ilya E. ^{[6
]}

Sokolovski, Sergei G. ^{[5
]}

Rafailov, Edik U. ^{[5
]}

机构：

[1] State Univ, Sci Educ Ctr Biomed Engn, Biomed Photon Instrumentat Grp, Educ Sci Prod Complex, Oryol 302020, Russia

[2] SPE LAZMA Ltd, Moscow 125252, Russia

[3] Priorov Cent Res Inst Traumatol & Orthopaed, Moscow 127299, Russia

[4] Minist Hlth Russian Federat, Endocrinol Res Ctr, Moscow 117036, Russia

[5] Aston Univ, Aston Inst Photon Technol, Optoelect & Biomed Photon Grp, Aston Triangle, Birmingham B4 7ET, W Midlands, England

[6] Aston Univ, Aston Inst Photon Technol, Sch Engn & Appl Sci, Aston Triangle, Birmingham B4 7ET, W Midlands, England

来源：

ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC AND SURGICAL GUIDANCE SYSTEMS XIV | 2016年 / 9698卷

关键词：

diabetic foot syndrome; microcirculation; redox ratio; fluorescence spectroscopy; laser Doppler flowmetry; TRANSCUTANEOUS OXIMETRY; NITRIC-OXIDE; RAT-HEART; SKIN; FLOW; FLUORESCENCE; ISCHEMIA; KINETICS; HUMANS; VIVO;

D O I：

10.1117/12.2212758

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.

引用

页数：7

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