Patterns of opioid use for chronic noncancer pain in the Veterans Health Administration from 2009 to 2011

被引:89
作者
Edlund, Mark J. [1 ,2 ]
Austen, Mark A. [3 ]
Sullivan, Mark D. [4 ]
Martin, Bradley C. [3 ,5 ]
Williams, James S. [3 ]
Fortney, John C. [3 ,6 ,7 ]
Hudson, Teresa J. [3 ,6 ]
机构
[1] RTI Int, Behav Hlth Epidemiol Program, Res Triangle Pk, NC 27709 USA
[2] St Lukes Hlth Syst, Behav Hlth Serv, Twin Falls, ID 83301 USA
[3] Cent Arkansas Vet Healthcare Syst, HSR&D Ctr Mental Healthcare & Outcomes Res, North Little Rock, AR 72114 USA
[4] Univ Washington, Sch Med, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA
[5] Univ Arkansas Med Sci, Div Pharmaceut Evaluat & Policy, Little Rock, AR 72205 USA
[6] Univ Arkansas Med Sci, Div Hlth Serv Res, Dept Psychiat, Coll Med, Little Rock, AR 72205 USA
[7] Cent Arkansas Vet Healthcare Syst, South Cent Mental Illness, Res Educ & Clin Ctr, North Little Rock, AR 72114 USA
关键词
Chronic noncancer pain; Opioids; Veterans; PRESCRIPTION OPIOIDS; OEF/OIF VETERANS; UNITED-STATES; ABUSE; RISK; CARE; ASSOCIATION; DEPENDENCE; OVERDOSE; THERAPY;
D O I
10.1016/j.pain.2014.08.033
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Although opioids are frequently prescribed for chronic noncancer pain (CNCP) among Veterans Health Administration (VHA) patients, little has been reported on national opioid prescribing patterns in the VHA. Our objective was to better characterize the dosing and duration of opioid therapy for CNCP in the VHA. We analyzed national VHA administrative and pharmacy data for fiscal years 2009 to 2011. For individuals with CNCP diagnoses and any opioid use in the fiscal year, we calculated the distribution of individual mean daily opioid dose, individual total days covered with opioids in a year, and individual total opioid dose in a year. We also investigated the factors associated with being in the top 5% of individuals for total opioid dose in a year, which we term receipt of high-volume opioids. About half of the patients with CNCP received opioids in a given fiscal year. The median daily dose was 21 mg morphine equivalents. Approximately 4.5% had a mean daily dose higher than 120 mg morphine equivalents. The median days covered in a year was 115 to 120 days in these years for those receiving opioids. Fifty-seven percent had at least 90 days covered with opioids per year. Major depression and posttraumatic stress disorder were positively associated with receiving high-volume opioids, but nonopioid substance use disorders were not. Among VHA patients with CNCP, chronic opioid therapy occurs frequently, but for most patients, the average daily dose is modest. Doses and duration of therapy were unchanged from 2009 to 2011. (C) 2014 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:2337 / 2343
页数:7
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