Ferric citrate: cardio- and renoprotective in chronic kidney disease?

被引：0

作者：

Hanudel, Mark R. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, Div Nephrol, Dept Pediat, Los Angeles, CA 90095 USA

来源：

KIDNEY INTERNATIONAL | 2019年 / 96卷 / 06期

关键词：

PHOSPHATE; IRON;

D O I：

10.1016/j.kint.2019.09.004

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Ferric citrate is a phosphate binder that may also be used to treat iron-deficiency anemia. In human studies, ferric citrate treatment in the setting of chronic kidney disease has been associated with effective phosphate control, improved iron and hematologic parameters, and decreased fibroblast growth factor 23 levels. In the present study, mice with chronic kidney disease treated with ferric citrate have similarly improved biochemical profiles, but also have improved cardiac and renal function and prolonged survival. Copyright (C) 2019, International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

引用

页码：1277 / 1279

页数：4

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