Toll-like receptor-4 signaling: a new potential therapeutic pathway for rheumatoid arthritis

被引：10
|
作者：
Li, Xiaofeng [1 ]
Xu, Tao [1 ]
Wang, Yarui [1 ]
Huang, Cheng [1 ]
Li, Jun [1 ]
机构：
[1] Anhui Med Univ, Sch Pharm, Hefei 230032, Anhui, Peoples R China
来源：
RHEUMATOLOGY INTERNATIONAL | 2014年 / 34卷 / 11期
关键词：
The toll-like receptor-4 signaling; Rheumatoid arthritis; Pro-inflammatory cytokines; EXPRESSION; TLR4;
D O I：
10.1007/s00296-013-2890-1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The Toll-like receptor-4 signaling (TLR-4) has been found to be over-expressed in rheumatoid arthritis (RA) synovium. Furthermore, it regulates the expression of pro-inflammatory cytokines. Based on the current evidences, TLR-4 may be a new potential therapeutic pathway for RA.
引用
收藏
页码：1613 / 1614
页数：2
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