Aziridines and aziridinium ions in the practical synthesis of pharmaceutical intermediates - A perspective

被引：0
作者：
Dahanukar, VH [1 ]
Zavialov, IA [1 ]
机构：
[1] Schering Plough Res Inst, Dept Synthet Chem, Union, NJ 07083 USA
来源：
CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT | 2002年 / 5卷 / 06期
关键词：
aziridination; aziridines; aziridinium ions; nucleophilic ring-opening reactions; pharmaceutical intermediates; process chemistry;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Recent methods for the synthesis of aziridines and aziridinium ions, the mechanisms of their nucleophilic ring-opening reactions and applications to the practical synthesis of pharmaceutical intermediates are reviewed.
引用
收藏
页码：918 / 927
页数：10
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