Sedative and antinociceptive effects of romifidine and xylazine in Thoroughbred mares

被引：6

作者：

Christovao, F. G. ^{[1
]}

Zamur, G. ^{[1
]}

Mataqueiro, M. I. ^{[1
]}

Queiroz-Neto, A. ^{[1
]}

机构：

[1] UNESP, Fac Ciencias Agrarias & Vet, BR-14884900 Jaboticabal, SP, Brazil

来源：

ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA | 2006年 / 58卷 / 06期

关键词：

horse; romifidine; xylazine; antinociception; sedation;

D O I：

10.1590/S0102-09352006000600009

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The sedative and antinociceptive effects of romifidine (0.1mg/kg) and of xylazine (1.0mg/kg) on Thoroughbred mares were studied. Sedation was evaluated by quantifying spontaneous locomotor activity (SLA) and head height (HH) in animals placed in automated individual behaviour stalls. Antinociception was determined utilizing a heat irradiation lamp recording the latency time for the hoof withdrawal reflex (HWRL) and the latency time for the skin twitch reflex (STRL) in a randomised block design with 10 replicates. Comparison of the sedative effects of romifidine and of xylazine on SLA showed a faster effect for xylazine. Regarding the sedative effect of the substances based on HH, romifidine caused a longer-lasting effect. Romifidine caused an increase in HWRL and STRL, and xylazine, an agent known for its analgesic effect, did not have an antinociceptive effect based on STRL result. The antinociceptive effect of romifidine was more pronounced than the xylazine effect.

引用

页码：1030 / 1036

页数：7

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