Gallstone disease

被引：179
作者：
Marschall, H.-U. [1 ]
Einarsson, C. [1 ]
机构：
[1] Karolinska Univ Hosp, Karolinska Inst, Dept Med, S-14186 Huddinge, Sweden
来源：
JOURNAL OF INTERNAL MEDICINE | 2007年 / 261卷 / 06期
关键词：
gastroenterology; hepatology;
D O I：
10.1111/j.1365-2796.2007.01783.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Gallstone disease is one of the most prevalent gastrointestinal diseases with a substantial burden to health care systems that is supposed to increase in ageing populations at risk. Aetiology and pathogenesis of cholesterol gallstones still are not well defined, and strategies for prevention and efficient nonsurgical therapies are missing. This review summarizes current concepts on the pathogenesis of cholesterol gallstones with focus on the uptake and secretion of biliary lipids and special emphasis on recent studies into the genetic background.
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收藏
页码：529 / 542
页数：14
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