Pleomorphic myxoid liposarcoma in an adolescent with Li-Fraumeni syndrome

被引：35

作者：

Sinclair, Tiffany J. ^{[1
]}

Thorson, Chad M. ^{[2
]}

Alvarez, Elysia ^{[3
]}

Tan, Serena ^{[4
]}

Spunt, Sheri L. ^{[3
]}

Chao, Stephanie D. ^{[2
]}

机构：

[1] Stanford Univ, Dept Surg, Sch Med, 300 Pasteur Dr Rm H3691, Stanford, CA 94306 USA

[2] Stanford Univ, Div Pediat Surg, Dept Surg, Sch Med, 300 Pasteur Dr,Alway Bldg M116,MC 5733, Stanford, CA 94305 USA

[3] Stanford Univ, Dept Pediat, Sch Med, Div Pediat Hematol Oncol, Stanford, CA 94305 USA

[4] Stanford Univ, Dept Pathol, Sch Med, 300 Pasteur Dr Rm L235, Stanford, CA 94305 USA

来源：

PEDIATRIC SURGERY INTERNATIONAL | 2017年 / 33卷 / 05期

关键词：

Sarcoma; TP53; mutation; Hereditary cancer syndrome; Li-Fraumeni syndrome; SOFT-TISSUE-SARCOMA; CHILDHOOD LIPOSARCOMA; MUTATION CARRIERS; CANCER; FAMILIES; TUMORS; CRITERIA; CHILDREN; GENE;

D O I：

10.1007/s00383-017-4063-x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We present the case of a 15-year-old female with a right perineal mass that was found to be pleomorphic myxoid liposarcoma, a recently recognized, rare subtype of liposarcoma. The patient had a strong family history of malignancy and genetic screening revealed a pathogenic TP53 mutation consistent with Li-Fraumeni syndrome.

引用

页码：631 / 635

页数：5

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