Electro-acupuncture attenuates nitric oxide release from rat striatum after transient middle cerebral artery occlusion

被引：23

作者：

Zhao, P ^{[1
]}

Huang, ZN ^{[1
]}

Chen, G ^{[1
]}

Cheng, JS ^{[1
]}

机构：

[1] Shanghai Med Univ, Inst Acupunture Res, Natl Lab Med Neurobiol, Shanghai 200032, Peoples R China

来源：

ACUPUNCTURE & ELECTRO-THERAPEUTICS RESEARCH | 2000年 / 25卷 / 02期

关键词：

electroacupuncture; middle cerebral artery occlusion; nitric oxide;

D O I：

10.3727/036012900816356163

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Nitric oxide (NO) is an important diffusible neurotransmitter, which also has neurotoxicity when it is overproduced. To investigate whether electro-acupuncture (EA) could inhibit the excessive NO release during cerebral ischemia, we detected NO directly by our self-made NO sensitive electrode. The electrode was placed into rat striatum after transient middle cerebral artery occlusion. NO level was significantly increased upon the onset of ischemia and reperfusion. EA apparently antagonized the ischemia-elicited rise of NO, although it could not suppress the NO level to baseline. The results indicated that EA might inhibit directly the elevation of NO following cerebral ischemia.

引用

页码：101 / 107

页数：7