In vivo three-dimensional microelectromechanical endoscopic swept source optical coherence tomography

被引:44
作者
Su, Jianping
Zhang, Jun
Yu, Linfeng
Chen, Zhongping [1 ]
机构
[1] Univ Calif Irvine, Dept Biomed Engn, Irvine, CA 92612 USA
[2] Univ Calif Irvine, Beckman Laser Inst, Irvine, CA 92612 USA
关键词
D O I
10.1364/OE.15.010390
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
In clinical applications, three-dimensional (3-D) microscopic image volume reveals tissue morphological changes, which are closely related to pre-cancer and early stage disease, much better than two-dimensional images. However, the traditional endoscope only achieves two-dimensional surface images. In this paper, a 3-D endoscopic microscope was developed based on a rotational microelectromechanical system (MEMS) probe [1]. The 3-D helix scan mode was realized by combining a MEMS motor rotational scan and linear stage transversal movement. In order to coordinate the high spin speed of MEMS motor inside the endoscope, an optical coherence tomography (OCT) system with a broadband fast swept laser was used. In vivo 3-D image volumes of rabbit esophagus and trachea were demonstrated. (c) 2007 Optical Society of America.
引用
收藏
页码:10390 / 10396
页数:7
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