Mucinous tubular and spindle cell carcinoma of the kidney: the contrast-enhanced ultrasonography and CT features of six cases and review of the literature

To report the features of contrast-enhanced ultrasonography (CEUS) and computer tomography (CECT) of mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney. Six cases of MTSCC of the kidney were studied, and the literature was reviewed. Ultrasonography, CEUS, and CECT examinations were routinely performed before the operation. Histological analysis, including HE staining and immunohistochemistry, was performed with the envision method. The age of the patients ranged from 48 to 75 years (mean 55.5 years). One patient was male, and five were females. All six tumours exhibited an admixture of tubules, spindle cells, and mucinous stroma in variable proportions. CEUS and CECT showed enhancement of the lesions, but the enhancement was less than the adjacent renal parenchyma, leading to the diagnosis of hypovascular renal tumours. All patients were alive and well at the follow-up time of 17-73 months (mean 39.5 months) with CEUS and/or CECT at 3 months, 6 months, and 1 year and then annually thereafter following surgery. No metastases were detected. The CEUS and CECT findings of MTSCC were generally hypovascular and needed to be distinguished from other hypovascular renal tumours.