Demethylases Go Mental

被引：5
作者：
Dawson, Mark A. [1 ,2 ,3 ,4 ]
Bannister, Andrew J. [1 ,2 ]
机构：
[1] Gurdon Inst, Cambridge CB2 1QN, England
[2] Dept Pathol, Cambridge CB2 1QN, England
[3] Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 0XY, England
[4] Univ Cambridge, Addenbrookes Hosp, Cambridge CB2 0XY, England
来源：
MOLECULAR CELL | 2010年 / 38卷 / 02期
关键词：
HISTONE LYSINE DEMETHYLASES; PHF8;
D O I：
10.1016/j.molcel.2010.04.002
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Histone-modifying enzymes require recruitment to specific genomic loci in order to elicit their effects. In this issue, Kleine-Kohlbrecher et al. reveal how a histone demethylase is targeted to specific genes, thereby providing mechanistic insight into recruitment and regulation.
引用
收藏
页码：155 / 157
页数：3
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